National effort to combat Alzheimer's disease begins; as research continues, there are preventive steps you can take

Country singer Glen Campbell, who has Alzheimer's disease,
stands with wife Kim during a national conference Tuesday.
Associated Press photo by Charles Dharapak.

With numbers expected to jump to 16 million Americans by 2050, research is being conducted in earnest to find a way to ward off Alzheimer's disease.

One plan of attack is testing therapies before people show symptoms of memory loss, since the disease starts attacking the brain at least 10 years before memory problems appear. An international study will see if an experimental drug can halt the disease in "people who appear healthy but are genetically destined to get a type of Alzheimer's that runs in the family," reports Lauran Neergaard for The Associated Press. In another study, researchers will see if a nasal spray that shoots insulin to the brain can help patients with early memory problems.

Part of the challenge in combatting the disease is researchers are still not sure what causes it. "The chief suspects are a sticky gunk called bata-amyloid, which makes up the disease's hallmark brain plaques, and tangles of a protein named tau that clogs up dying brain cells. One theory: "Amyloid may kick off the disease while tau speeds up the brain destruction," Neergaard reports.

Given the expected increase in the number of people with Alzheimer's, the Obama administration has adopted a national strategy to fight the disease, part of which is a website that is a "one-stop shop for families" to offer information about dementia and links to community resources. Today, there are 5.4 Americans with Alzheimer's or related dementias.

There are steps people can take to protect their brains from the disease, including intellectual and social stimulation to help build "cognitive reserve." Doing crossword puzzles, for example, can help. So can physical activity. "Any time your heart is healthier, your brain is healthier," said Dr. Elizabeth head of the University of Kentucky. Diet is another consideration, since foods that are heart healthy are brain healthy, including omega-3 fatty acids found in fish. (Read more)

Doctors use telemedicine to help patients with dementia, Alzheimer's

Following a nationwide trend, Kentucky doctors are turning to telemedicine to help patients with memory problems such as those associated with Alzheimer's disease and dementia, reports Allison Elliott with the University of Kentucky.

"State-of-the-art memory evaluations should not be limited to persons that are able tom ake the often long and arduous trip to Lexington," said Dr. Greg Jicha, neurologist at UK's Sanders-Brown Center on Aging. "Taking advantage of Internet technologists to bring expert care into even the smallest of rural communities is a blessing for many families across Kentucky that simply cannot bring a loved one with dementia to Lexington.

Several times a month, physicians with the Sanders-Brown Center will connect to patients in clinics throughout the state. Participating clinics include Harlan Appalachian Regional Health; the Hazard Center for Rural Health; T.J. Sampson Hospital in Glasgow; Trover Clinic in Madisonville; Western Baptist Hospital in Paducah; Owensboro Medical Center; and St. Claire Regional Medical Center in Morehead. (Read more)

Free conference on Alzheimer's in Louisville Sept. 17

A Washington-based geriatric researcher will join University of Louisville researchers and clinicians a free conference examining Alzheimer’s disease from 9 a.m. to 3 p.m., Saturday, Sept. 17, at the Crowne Plaza Louisville Airport Hotel, 830 Phillips Lane, near the state fairgrounds.

“The Journey: Alzheimer’s Disease and Caregiving” will provide information on the risk factors for Alzheimer’s disease, the reasons why certain populations are at greater risk for developing it, and current practices in caregiving. Admission, parking and lunch are free to participants at but pre-registration is required by Sept. 15 to info@alz.org or 1-800-272-3900.

Thomas Obisesan, M.D., chief of geriatrics at Howard University Hospital, will open the meeting. His research is focused on finding a cure for Alzheimer’s and "disentangling the overlap of cardiovascular disease with Alzheimer’s disease risk," a U of L release says. The conference is supported with grants from Eisai Co. Ltd. and the Signature Research Institute. It is co-sponsored by the university and the Greater Kentucky and Southern Indiana Chapter of the Alzheimer’s Association.

UK gets $7 million for Alzheimer's research

The University of Kentucky has received a $7 million grant to continue its research on Alzheimer's disease. The research is conducted at the Sanders-Brown Center on Aging and involves clinical trials and comparing brains diseased by Alzheimer's to those that are not.

"It is the second major grant announcement for UK in two days," reports the Lexington Herald-Leader's Cheryl Truman. "On Monday, UK received a $14.5 million grant to develop pollution-catching technologies for coal-fired power plants."

The grant proves UK "is not only able to compete among the big boys but be one of the big boys" when it comes to Alzheimer's research and treatment, said Michael Karpf, UK's executive vice president of health administration.

At the Sanders-Brown center, more than 700 research volunteers from around Kentucky take part in clinical trails and a brain donation program, which allows researchers to compare Alzheimer's-affected brains to those that aren't. (Read more)