Brains of autistic children develop differently, study finds

MRI image of young brain in study

Researchers have found significant differences in brain development starting at age 6 months in high-risk infants who develop autism compared to those who don't. The finding suggests the disorder develops over time and doesn't have a sudden onset, which is often believed to be the case.

"It's a preliminary, albeit great, first step towards thinking about developing a biomarker for risk in advance of our current ability to diagnose autism," said Jason J. Wolff, lead author of the study.

The study may be useful for journalists writing new stories about autistic children and their parents; April is National Autism Awareness Month. It raises the possibility "that we may be able to interrupt that process with targeted intervention," Wolff said.

Participants in the study, which was published online in the Advance section of the American Journal of Psychiatry, included 92 infants who have older siblings with autism and so were considered at high risk for developing the disorder. They were tested using a type of MRI at 6 months of age and had behavioral assessments done at 24 months. Most of the infants also had more brain-imaging scans at either or both 12 and 24 months of age, reports research-reporting service Newswise.

At 24 months, 28 infants — 30 percent — fell into the autism disorder spectrum, while 64 did not. "The two groups differed in white matter fiber tract development — pathways that connect brain regions — as measured by fractional anisotropy," Newswise reports.

Based on the way water molecules move through brain issue, fractional anisotrophy measures the way white matter is organized and develops. In 12 of the 15 tracts of children who did develop autism, there were significant FA trajectories. "This evidence, which implicates multiple fiber pathways, suggests that autism is a whole-brain phenomenon not isolated to any particular brain region," Wolff said. (Read more)

Vaccines

Excerpt from Dr. Mercola May 22, 2011
American prosecutors are attempting to extradite a Danish scientist.

Poul Thorsen has been charged with 13 counts of wire fraud and nine counts of money laundering; a federal grand jury alleges that Thorsen stole over $1 million from autism research funding between February 2004 and June 2008.

Thorsen is said to have used the proceeds to buy a home in Atlanta, two cars and a Harley Davidson. He is said to have stolen the money while serving as the 'principal investigator' for a program that studied the relationship between autism and exposure to vaccines.

The Copenhagen Post reports:

"... [O]ver the four-year period he submitted over a dozen false invoices from the CDC for research expenses to Aarhus University, where he held a faculty position, instructing them to transfer the funds to a CDC account, which was in fact his personal account ...

Thorsen's research on autism is widely known in academic circles, where he was until this week a highly respected figure. A paper of his on the subject, which is known as 'The Danish Study', is quoted extensively to refute the autism vaccine connection."

Another prominent name in vaccine medicine, Dr. Paul Offit, well-known shill for the vaccine industry, has also been called out for making false and unsubstantiated statements about CBS News Investigative Correspondent Sharyl Attkisson and her report looking into the ties between vaccine supporters and the vaccine industry.

On April 18, 2011, the California Orange County Register issued a retraction of an August 4, 2008 article containing disparaging statements made by Dr. Offit about Attkisson.

According to Adventures in Autism:

"Upon further review, it appears that a number of Dr. Offit's statements, as quoted in the OC Register article, were unsubstantiated and/or false. Attkisson had previously reported on the vaccine industry ties of Dr. Offit and others in a CBS Evening News report 'How Independent Are Vaccine Defenders?'"

The unsubstantiated statements included a claim that Attkisson "lied", and a claim that CBS News sent a "mean spirited and vituperative" email. Offit also told the OC Register that he provided CBS News "the details of his relationship ... with pharmaceutical company Merck", but documents provided by CBS News indicate Offit did not disclose all of his financial relationships with Merck.

Sources:
Atlanta Journal Constitution April 14, 2011

WKAR Atlanta April 13, 2011

The Copenhagen Post April 15, 2011